Saquon Barkley injury update: Giants star (ankle) officially ruled out for PatriotsSporting News — (Kirstie Chiappelli)
Giants running back Saquon Barkley has been officially ruled out of Thursday night's game against the Patriots as he continues to rehab his high ankle sprain, the team announced Wednesday.
Barkley was able to return to practice last week but apparently was unable to get medical clearance to play this week.
The Giants also will be without receiver Sterling Shepard, who is in the league's concussion protocol for the second time this season, tight end Evan Engram, the team's leading receiver (373 yards) who is dealing with a sprained MCL, and running back, Wayne Gallman, Barkley's top backup who also is in the concussion protocol.
The injuries leave New York short-handed against the league's top-ranked defense, an undesirable scenario for rookie quarterback Daniel Jones' first meeting with New England.
Barkley reportedly said he could beat his initial four- to eight-week timetable for recovery, but the Giants staff is taking a cautious approach in easing him back into action.
The 2018 NFL Offensive Rookie of the Year injured his ankle in the second quarter of the Giants' Week 3 win over the Buccaneers.
Despite missing the past two games entirely and most of the game in which he was injured, Barkley still leads the Giants in rushing with 237 yards. Gallman is next with 107. Jones will enter Thursday's game as the team's active rushing leader with 78 yards, 25 more than projected starting running back Jon Hilliman.
The Giants (2-3) will visit the undefeated Patriots at 8:20 p.m. ET Thursday.